Thank you to everybody for the responses! Informative and hugely helpful.
Dino De Laurentiis King Kong - I was actually oddly enamored by this. I think the people I was watching it with had set my expectations so low that I couldn't be underwhelmed. But I thought the visual effects were just the right balance of epic and campy.
The Room - So much of this has already disseminated, I'm trying to keep away from movies that everyone has already had some exposure to (if only in meme form) unless I can think of some fresh take on it. Though I will most likely get to it at some point.
Delgo - I love the 'anti-Mariachi' sentiment. Never seen this one either, is it any good on its own terms?
The Last Mimzy - Again, perfect example, and I never knew about the history. Thanks!
The Conqueror - This has been on my mental list for a while, I really need to get around to watching it.
A*P*E - I'm guessing that image doesn't ever actually occur...
Troll 2 - Totally agree in terms of infamy, but I think 'Best Worst Movie' has already closed the book on that one, I feel like anything I could say would be redundant at this point.
Lady In The Water - Agreed, that would be a great 'in' for talking abut M. Night's ballooning ego and everything.
Manos & Birdemic - Are both on my vague mental list, I'm trying to think of an interesting angle to examine them from. Apart from being made on a bet, does Manos have any other weird circumstances surrounding it? I guess 'made on a bet' is probably weird enough.
Pulgasari - I have a copy of it, planning to watch soon. Definitely one of the best 'weird production history' stories.
Howard The Duck - I have a crazy theory about this movie where if all of the dialogue was delivered in deadpan instead of telegraphing every joke in a sitcom way, it would be hilarious. It's also on my mental list, it definitely fits that bill of just blowing your mind with the amount of money and effort spent VS product. Especially with that fantastically realized stop motion at the end.
Thanks again for the suggestions, you are kings among message boarders.