The "Duke" (Charles Grodin) in Midnight Run. He stole a ton of money from the Mafia boss he unwittingly worked for and gave it to charity and then seems genuinely concerned for the health, both emotional and physical of the bounty hunter sent to get him. He's also unfailingly polite to everyone.
The Gundersons (Frances McDormand and John Carrol Lynch) in Fargo. In the bleak sea of noir that is the universe of Fargo, these two people lead quiet and decent lives and very much love each other. Their final conversation in bed at the end as Norm tells Marge that his art is going to be on the 3 cent stamp always makes me smile.
Joshua in Lamb by Christopher Moore
Well, duh, he's Jesus, but a totally relatable Jesus. He loves everyone, but especially his friends Biff and Maggie and has nothing but good intentions, facing his fate with grace. He has the same fears and temptations as we all do, but handles them with humor and humility. Joshua is just a great dude.
George Michael Bluth in Arrested Development (Michael Cera)
The only Bluth I could imagine growing into a genuinely good adult. Even his dad, the more or less decent Michael Bluth has his moments of dickishness(His treatment of Anne Veal for one) Sure, he has his quirks and issues, like his weird crush on his cousin, but he's a teenager, awkwardness and quirks comes with the territory. He's a nice kid and doesn't like to hurt anyone.
(page from Hitman #34, one of the best Superman stories ever)
Edited by Cameron Hughes - 8/1/12 at 6:21pm